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We established a sensitive LC-MS/MS method for quantification of 1,2-propylene glycol (PG) and glycerol (G) in plasma and urine samples from users of different nicotine products, including combustible cigarettes (CC), ECs, heated tobacco products (HTP), oral tobacco (OT), and oral/dermal nicotine delivery products used for nicotine replacement therapy (NRT), and a control group of non-users (NU)

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However, for drugs like stimulants or cannabis, there are currently no FDA-approved medications available, and therapy becomes the primary approach [4]

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